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Our Projects


Current Studies

A Mobile Health Intervention in Pulmonary Arterial Hypertension (mHealth)

We have partnered with the Vanderbilt University Medical Center as co-investigators in an ongoing study which proposes the use of a mobile health intervention to encourage increased exercise in PAH patients. The study is a randomized trial to examine the feasibility of leveraging a wearable activity tracker (Fitbit Charge HR) and a text messaging intervention to increase physical activity.

​The design of this intervention was derived from our original mActive study. Personalized messages (“smart texts”) evaluate and incorporate real-time activity data from Fitbit devices in the selection of message types and content.

For more information on this study, visit:
clinicaltrials.gov/ct2/show/NCT03069716?term=03069716&rank=1 

Interventions Against Insulin Resistance in Pulmonary Arterial Hypertension

In addition, we are also partnering with the Vanderbilt University Medical Center on a study evaluating whether interventions to prevent insulin resistance (i.e. metformin and the mActive text messaging intervention) in patients with PAH will also improve exercise capacity.

For more information on this study, visit:
https://clinicaltrials.gov/ct2/show/record/NCT03617458

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Past Studies

mActive Trial

This intervention trial showed that our automated tracking-texting intervention increased physical activity with, but not without, the texting component. Smart texts increased physical activity by about a mile per day.

Learn more about the mActive Trial here:
https://clinicaltrials.gov/ct2/show/NCT01917812
http://jaha.ahajournals.org/content/4/11/e002239.full


We are currently performing long-term follow-up of mActive trial participants, with support from the Aetna Foundation.
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mActive-Smoke

In this observational study, supported by the American Heart Association, we used mHealth tools to study the longitudinal association of physical activity with smoking urges.
​
Read more about the results here.

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Selected Publications

2018
  • mActive-Smoke: A Prospective Observational Study Using Mobile Health Tools to Assess the Association of Physical Activity with Smoking Urges.
2016
  • One Year Follow-up of the mActive Randomized Clinical mHealth Trial of Physical Activity
  • Validation of the Instant Blood Pressure Smartphone App

2015
  • ​Mobile Health Initiatives to Improve Outcomes in Primary Prevention of Cardiovascular Disease

2014
  • Recruitment success of the mActive Physical Activity mHealth Trial: Can Convenience Increase Enrollment of Eligible Patients and Women Into RCTs? ​
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Awards

  • Steven N. Blair Excellence in Physical Activity Research Award​

  • Howard S. Silverman Award for originality and creativity in medical research
 
  • American Heart Association Best of Specialty Conferences Award for top scoring abstract
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  • Stanley L. Blumenthal Research Award
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